Rationale

Prevention and treatment of venous thromboembolism (VTE) in patients with cancer require the coordinated efforts of internists, oncologists, hematologists, vascular medicine specialists, and nurses, highlighting the importance of multidisciplinary management approaches. The ITAC international clinical practice guidelines have contributed to disseminate knowledge and to reduce practice gaps among physicians, aiming to improve adequate treatment and prophylaxis of VTE in patients with cancer globally. Thus, international education programs are necessary to disseminate information on the risks associated with VTE in patients with cancer, the urgency of timely prophylaxis and effective treatment of established VTE, and actionable guidance on regularly updated consensus ITAC guidelines.

VTE presents an additional challenge for clinicians treating patients with cancer. Cancer-associated thrombosis (CAT) recurrence and bleeding rates under anticoagulant treatment are higher in individuals with cancer compared to VTE patients without cancer. Clinicians face a growing number of treatment choices for individual cancer patients with VTE. A personalized approach based on the best anticoagulation regimen according to each drug efficacy and safety profile, and to patient preference is warranted. This can be facilitated by using the free interactive ITAC guideline mobile app, currently available for i0S and Android, in English, French, Spanish, Portuguese and Russian.